circRNA
Preserve the circle. Address open RNA species and duplex impurities.
TECHNOLOGY / MGA
Enter the
molecular landscape
Explore the MGA architecture, our RNA purification programs, and the electrical signatures behind our approach to impurity characterization.
MGA / PLATFORM OBSERVATORY01 — SURFACE
A structured landscape
The conceptual model requires a browser with 3D graphics support. Explore the four perspectives and their descriptions below.
ELECTRICAL RESPONSE
A molecular interaction signature
01 / ACQUIREElectrical response02 / COMPUTEPattern analysis03 / CHARACTERIZEImpurity profile
Impurity profile
PRODUCT VISIONcircRNA purification
Open RNA species
Duplex impurities
Interaction diversity
CIRCULAR PRODUCT / OPEN & DUPLEX IMPURITIES
Conceptual signatures · not experimental measurements
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Illustrative architecture · layout, proportions, and layers are abstractedPhysical prototypes built
01 / A PHYSICAL PLATFORM
An environment engineered
for molecular interactions
MGA brings molecular science into a structured microscale environment. We have fabricated and studied MGA arrays in the laboratory.
The illustration conveys the character of a post array. Its arrangement and proportions do not reproduce a working device.
RNA PURIFICATION / circRNA & mRNA
The right RNA
In its right form
Preserve the circle
Resolve what surrounds it
Our circRNA program targets the intact circular product in mixtures containing open RNA species and duplex impurities. Our mRNA program focuses on dsRNA impurity removal.
MGA prototypes have demonstrated differential retention and surface capture in DNA model systems. This experimental foundation guides our work on circRNA and the broader RNA purification roadmap.
mRNA / dsRNA
Preserve the messenger. Target double-stranded RNA impurities.
01
Purity
Target open RNA species and duplex impurities.
02
Integrity
Keep the intact circular product at the center.
03
Process
Evaluate recovery, purity, and repeatability in relevant RNA samples.
A SECOND PERSPECTIVE / ELECTRICAL SENSING
A signal acquired
A profile revealed
Our product vision brings purification and characterization into the same workflow: acquire electrical responses, analyze interaction patterns, and resolve an impurity profile.
Explore the characterization view ↑Understand
the impurity landscape
Computational analysis connects molecular interaction signatures with the species surrounding a valuable RNA product.
01 Acquire the electrical response
02 Resolve patterns in the signal
03 Characterize the impurity profile
Different products
Deeper understanding
Characterize open and duplex species around circRNA. Extend the same product vision to dsRNA impurities in mRNA purification.
The signal-to-profile experience presents the intended product workflow. Its signatures are conceptual, not experimental measurements or validated assay results.
Discuss a sensing collaboration ↗THE EXPERIMENTAL FOUNDATION
Physical prototypes
Observed molecular behavior
Fabricated arrays and microscopy studies have established the platform’s experimental foundation in DNA model systems.
Our RNA programs evaluate product-specific performance, including purity, recovery, and repeatability.
WORK WITH ZOLX
Advancing purification
Deeper understanding
Connect with our team on RNA purification, impurity characterization, and process development.
Start a conversation ↗