A physical platform
MGA arrays fabricated and studied in the laboratory.
MGA
MGA
Molecular separation & characterization
RNA PURIFICATION & CHARACTERIZATION
The future
of RNA comes
full circle
We’ve built Mechanically-Gated Adsorption (MGA), a physical platform for molecular separation and impurity characterization.
Discover the landscape ↓01 / THE ARCHITECTURE
Precision
takes shape
MGA brings engineered surfaces and molecular science together in a physical device. Built in the laboratory. Driven by a new approach to separation.
Engineered for separation and characterization.
02 / RNA PURIFICATION
Preserve
the circle
Our circRNA purification program targets the intact circular product while addressing open RNA species and duplex impurities.
Preserve valuable RNA. Resolve the species around it.
03 / ELECTRICAL SENSING
Molecular signals
Impurity insight
Separation is only part of the story. Electrical responses open a path to characterizing the impurities around the RNA product.
circRNA Open & duplex impuritiesmRNA dsRNA impurity removal
Enter the signal view ↗04 / IMPURITY CHARACTERIZATION
Read between
the signals
Turn molecular interaction signals into an impurity profile. Our product vision connects purification with a deeper understanding of each sample.
CONCEPTUAL MOLECULAR ARCHITECTURE
circRNA Other RNA species
01 / ACQUIREElectrical response02 / COMPUTEPattern analysis03 / CHARACTERIZEImpurity profile
Impurity profile
PRODUCT VISIONcircRNA purification
Open RNA species
Duplex impurities
Interaction diversity
CIRCULAR PRODUCT / OPEN & DUPLEX IMPURITIES
Conceptual signatures · not experimental measurements
Architecture & molecular motion
Stylized to protect proprietary detail
RNA PURIFICATION & CHARACTERIZATION
Molecular separation
with deeper insight
The circle matters. So does everything around it.
MGA brings a physical approach to RNA purification and an electrical perspective on molecular interactions. Our programs address circRNA purification and dsRNA impurities in mRNA.
Inside our circRNA program ↗FROM PHYSICAL PROTOTYPES TO A PLATFORM
Built
Observed
Advancing
Molecular differences, made visible
Differential retention and surface capture demonstrated in DNA model systems.
RNA purification
Applying that experimental foundation to circRNA and mRNA purification.
APPLICATIONS & SECTORS
One physical platform
Multiple separation challenges
RNA purification, biomanufacturing, diagnostics, and materials.
Explore the separation challenges informing MGA development.
RNA THERAPEUTICS / PURIFICATION
Preserve the product
Resolve the impurities
Our RNA programs address circRNA purification and removal of dsRNA impurities from mRNA. Preserve valuable product. Resolve the species that don’t belong.
RNA purification programs
WORK WITH ZOLX
Advancing purification
Deeper understanding
Connect with our team on RNA purification, impurity characterization, and process development.
Start a conversation ↗